Hey Trevor,
I also goofed up and had the same error popping on me.  
Here is what was missing (written loud & clear in the documentation)

Run a2mod 
debox:/var/www/siremis-2.0.0# a2mod 

type "rewrite" when prompted.

Restart apache2
/etc/init.d/apache2 restart.


Cheers
--
X


On Tue, Nov 2, 2010 at 8:27 PM, Trevor Francis <trevor.francis@tgrahamcapital.com> wrote:
Not Found

The requested URL /siremis/system/general_default was not found on this server.

Apache/2.2.8 (Ubuntu) PHP/5.2.4-2ubuntu5.12 with Suhosin-Patch Server at 74.208.174.183 Port 80


I have tested this on both Firefox and Safari.


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