I'm testing with this kamailio version:

$ kamcmd version
kamailio 5.5.4 (x86_64/linux) 54c9df

on:

$ cat /etc/issue
Debian GNU/Linux 11 \n \l

with:

$ openssl version
OpenSSL 1.1.1k 25 Mar 2021

Whenever I start kamailio I get 3199 log lines like this:

2022-03-10T10:04:39.700676+09:00 lab002201-flip-server /usr/local/src/git/kamailio-5.5/src/kamailio[261703]: CRITICAL: <core> [core/mem/q_malloc.c:519]: qm_free(): BUG: freeing already freed pointer (0x7f8eb57f7848), called from tls: tls_init.c: ser_free(323), first free tls: tls_init.c: ser_free(323) - ignoring

I searched the issues at github and found:
https://github.com/kamailio/kamailio/issues/2560
https://github.com/kamailio/kamailio/issues/2912

So I tried to start kamailio with

--atexit=no
but those logs remain.

With and without using --atexit=no there is no crash and all my tests are OK.

But should I be worried to put this in production?