I catched issue with 
In the Kamailio logs i see

ssl bug #1491 workaround: not enough memory for safe operation: shm=10219080 threshold2=11796480

Current stat about shared memory

[root@sbc-a1 ~]# kamctl stats shmem
{
  "jsonrpc":  "2.0",
  "result": [
    "shmem:fragments = 528",
    "shmem:free_size = 11343104",
    "shmem:max_used_size = 124449952",
    "shmem:real_used_size = 122874624",
    "shmem:total_size = 134217728",
    "shmem:used_size = 58728144"
  ],
  "id": 703182
}

But when kamailio started

[root@sbc-a1 ~]# kamctl stats shmem
{
  "jsonrpc":  "2.0",
  "result": [
    "shmem:fragments = 122",
    "shmem:free_size = 112534264",
    "shmem:max_used_size = 22372528",
    "shmem:real_used_size = 21683464",
    "shmem:total_size = 134217728",
    "shmem:used_size = 12833888"
  ],
  "id": 703670
}

What is stange a lot of fragments.
How it can be troubleshooted?
Can memory manager show info about each fragment like when fragment are created an and which module requested fragment?