This ended up being a log file permissions issue. However this worked with root permission only - exec_msg("echo ‘TEST’ > /usr/local/etc/kamailio/test.txt"); This syntax was correct - exec_msg("/usr/local/etc/kamailio/script.py ‘arg1’ ‘arg2’ ‘arg3’"); Thanks for the input. -dan From: sr-users [mailto:sr-users-bounces@lists.kamailio.org] On Behalf Of otron2016(a)gmail.com Sent: Monday, December 11, 2017 10:08 AM To: Kamailio (SER) - Users Mailing List &lt;sr-users(a)lists.kamailio.org&gt; Subject: Re: [SR-Users] Exec - call python script with arguments Probably not the problem though it could be. ...try: "python /usr/local/etc/kamailio/script.py<http://script.py/> arg1 arg2 arg3" instead--kamailio doesn't have your shell env and might not pass the script to python even if the script has the #! declaration. Also, if you pasted the exact command I think there's no space between .py and arg1 (or that could just be my phone). Hth. Sent from Samsung Mobile -------- Original message -------- From: "Daniel W. Graham" <dan@cmsinter.net<mailto:dan@cmsinter.net>> Date: 12/10/2017 1:04 PM (GMT-06:00) To: "Kamailio (SER) - Users Mailing List" <sr-users@lists.kamailio.org<mailto:sr-users@lists.kamailio.org>> Subject: [SR-Users] Exec - call python script with arguments Trying to call a python script using exec_msg and haven’t had any luck. The following works: exec_msg("echo ‘TEST’ > /usr/local/etc/kamailio/test.txt"); The following works from shell: /usr/local/etc/kamailio/script.py arg1 arg2 arg3 The following does not work from kamailio: exec_msg("/usr/local/etc/kamailio/script.py arg1 arg2 arg3"); (The arguments are just strings for test purposes) Kamailio is running as kamailio user Permissions: 755 script.py Any idea what could be going wrong? -dan